单细胞奥米克分析揭示了COVID-19和HIV的免疫失调:通过未折叠的蛋白质反应和使用机器学习算法诊断生物标记物识别B细胞激活的共享异常

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Feng Li1, Wei Zhao1, Hong Liu1

  • 1School of Pharmacy, Key Laboratory of Nano-carbon Modified Film Technology of Henan Province, Diagnostic Laboratory of Animal Diseases, Xinxiang University, Xinxiang, Henan, China.

Journal of medical virology
|August 4, 2025
PubMed
概括

与COVID-19和HIV的同时感染显示出类似的细胞变化和共同的B细胞通路激活. 一个机器学习模型使用这些分子洞察力准确地诊断出这两种感染.

关键词:
根据COVID-19的情况,艾滋病病毒 艾滋病病毒 艾滋病病毒机器学习模型机器学习模型单细胞测序分析分析不折叠的蛋白质反应反应

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