在接受全关节关节整形手术的患者中,急性损伤的危险因素
Hazal Nur Kılıc1, K Sanem Cakar Turhan2, Suheyla Karadag Erkoc2
1Department of Anesthesiology and Reanimation, Duzıcı State Hospital, Turkish Ministry of Health, 80600 Osmaniye, Türkiye.
Reports (MDPI)
|August 4, 2025
概括
这项研究确定了关节置换手术后急性损伤 (AKI) 的关键风险因素. 晚年,并发症和某些药物,如NSAIDs增加了AKI风险.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 整形外科手术 整形外科手术
- 麻醉学 麻醉学
背景情况:
- 手术后的急性损伤 (AKI) 是全关节关节整形术后的一个重大并发症.
- 识别风险因素对于患者管理和改善结果至关重要.
研究的目的:
- 为了调查在全关节关节整形术后AKI的发生率.
- 在这个患者群体中确定与AKI相关的独立风险因素.
主要方法:
- 在2015年至2020年间,对911名接受关节形手术的患者进行了回顾性分析.
- 排除患有先前存在的功能衰竭的患者.
- 评估人口统计数据,并发病,手术因素和外科手术变量;用于预测的机器学习模型.
主要成果:
- 在14.7%的患者中检测到AKI (134/911).
- 确定的独立危险因素包括晚年,美国麻醉师协会 (ASA) 高分,高查尔森并发症指数 (CCI),高血压,糖尿病,手术前贫血以及使用NSAID,万科和对比剂.
- 后勤回归实现了最好的预测性能,达到85.2%.
结论:
- 晚年,高ASA和CCI,糖尿病,高血压和特定的外科手术后暴露是AKI的独立风险因素.
- 手术前的贫血和使用NSAID,万科米辛和对比剂的使用是AKI风险的重要贡献者.
- 这些发现可以为在接受关节形手术的患者中减轻AKI的策略提供信息.
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