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在患有多发性硬化症的人群中,有或没有血流限制的抵抗运动后,中央和外周疲劳指数

Ethan C Hill^1,2, Christopher E Proppe³, Sean M Lubiak¹

¹School of Kinesiology & Rehabilitation Sciences, University of Central Florida, Orlando, Florida, United States.

Journal of neurophysiology

|August 4, 2025

概括

低负荷阻力运动与血液流量限制 (LLBFR) 独特地增加了多发性硬化症 (PwMS) 患者的外周疲劳. 这种方法可以通过诱导较大的代谢压力来提高运动效率,而不是高负荷或标准低负荷抵抗训练.

科学领域:

神经学神经学
运动生理学运动生理学
康复科学康复科学康复科学

背景情况:

肌肉疲劳,以中央和外周机制为特征,是多发性硬化症 (PwMS) 患者面临的重大挑战.
抵抗运动对PwMS有好处,但对管理疲劳的最佳方案仍在研究中.
运动期间的血流限制 (BFR) 是一种新兴的策略,可以增强训练适应能力.

研究的目的:

为了比较低负荷 (LL),低负荷与血流限制 (LLBFR) 和高负荷 (HL) 阻力运动对PwMS中中心和外周疲劳的影响.
在临床上相关的背景下研究不同抵抗运动模式的疗效.

主要方法:

15名患有多发性硬化症的参与者使用HL (70% 1RM),LL (30% 1RM) 和LLBFR协议进行单边腿部延伸.
运动前和运动后测量了最大自发同度收缩 (MVIC) 扭矩,表面电动图 (sEMG) 振幅,叠加的抽扭矩 (STT) 和潜在的抽扭矩 (PTT).

主要成果:

所有的炼方案都导致了MVIC扭矩的显著下降.
与HL相比,LLBFR诱导的PTT (外周疲劳) 的减少明显更大.
在这些条件之间,没有观察到中央疲劳指数 (STT,sEMG振幅,V_WAVE/M_WAVE) 的显著差异.

结论:

对于PwMS来说,LLBFR可能是一个更有效的抵抗运动策略,因为它显著增加了周围疲劳,这是代谢压力的潜在指标.
这种方法可以提供创新的方法来改善多发性硬化症患者的炼结果.
进一步的研究应该探索LLBFR在PwMS中的长期影响和最佳应用.

关键词:

在 BFR 中,BFR 是 BFR 的代码.肌肉肌肉肌肉肌肉肌肉神经神经系统的神经系统康复康复康复康复康复康复强度强度强度强度强度强度强度强度强度强度强度强度强

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