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Updated: Sep 12, 2025

Author Spotlight: Achieving High-Purity In Vitro Differentiation of Th17 Cells Using Cytokine Concentration Modulation
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免疫反应基因1:中枢神经系统自身免疫中的Th17细胞致病性的线粒体关键

Mohammad Nematullah1, Mena Fatma1, Guoli Zhou2

  • 1Department of Neurology, Henry Ford Health System, Detroit, MI 48202.

Proceedings of the National Academy of Sciences of the United States of America
|August 4, 2025
PubMed
概括

免疫反应基因1 (Irg1) 保护中枢神经系统免受多发性硬化症等自身免疫性疾病的影响. 失去Irg1会通过促进致病的Th17细胞分化,加剧实验性自身免疫脑膜炎.

关键词:
欧洲电子商务管理局 (EEAE)的 IL1b 类型.在Irg1上,我们可以使用Irg1.Th17 这是一个很好的方法.我们的 scRNAseqq.

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