一篇关于静脉病动脉血流模拟的评论
G Shankar1, Dharmendra Tripathi2, P Deepalakshmi1
1Department of Mathematics, College of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur 603203, Tamil Nadu, India.
Critical reviews in biomedical engineering
|August 4, 2025
概括
本综述探讨了狭窄动脉中血流的数学和数值建模. 它强调了了解心血管疾病发病和患者减轻策略的进展.
科学领域:
- 心血管流体动力学心血管流体动力学
- 生物医学工程 生物医学工程
- 数学建模的数学建模
背景情况:
- 心脏病,包括中风和心脏病发作,通常是由动脉收缩 (缩小) 引起的血液流动中断引起的.
- 动脉样硬化和斑块积累是狭窄的常见原因,影响全球健康.
- 理论和计算研究补充了临床研究,为血液动力学障碍提供了洞察力.
研究的目的:
- 审查最近的数学和数值建模在狭窄动脉内血流的进展.
- 扩大对心血管疾病发病和患者缓解策略的理解.
- 为多学科研究人员提供全面的资源.
主要方法:
- 评价来自知名期刊的近期100多篇文章.
- 专注于建模,数值模拟和血液动力学特征评估的方法.
- 2015-2025年的几何和血液行为 (流体) 的表格组织.
主要成果:
- 在各种假设下 (流体模型,动脉特征,溶液技术) 探索了狭窄血液动力学的不同方面.
- 考虑了多物理效应,如传热,质量扩散和纳米粒子效应.
- 提供了与心血管疾病相关的血液动力学和缓解策略的复杂见解.
结论:
- 数学和数值建模显著提高了对狭窄动脉血流的理解.
- 这些研究为预测疾病发病和制定缓解策略提供了宝贵的见解.
- 该评论是数学家,生物工程师,计算机科学家和医学研究人员的重要资源,概述了未来的研究方向.
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相关概念视频
Blood Flow
Blood is pumped by the heart into the aorta, the largest artery in the body, and then into increasingly smaller arteries, arterioles, and capillaries. The velocity of blood flow decreases with increased cross-sectional blood vessel area. As blood returns to the heart through venules and veins, its velocity increases. The movement of blood is encouraged by smooth muscle in the vessel walls, the movement of skeletal muscle surrounding the vessels, and one-way valves that prevent backflow.
Autoregulation of Blood Flow
Autoregulation mechanisms are characterized by their inherent capacity for self-regulation without necessitating specific nervous stimulation or endocrine control. These mechanisms facilitate the adjustment of blood flow and, therefore, perfusion specific to each tissue region. This self-regulation encompasses chemical signals and myogenic controls.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
Chemical Signaling in Autoregulation
Chemical signaling operates at the precapillary sphincter level, inciting either contraction or relaxation.
