临床放射学变量与急性缺血性中风开始到成像时间之间的关联:一项回顾性研究
Bafrin Abdulmajid1, Laura M van Poppel2, Charles B L M Majoie2
1Department of Radiology and Nuclear Medicine, Amsterdam UMC, Amsterdam, the Netherlands.
概括
对于具有未知发病的急性缺血性中风患者,较低的ASPECTS和白血病表示较晚的成像时间. 然而,临床放射学变量在预测这些晚期发作到成像时间方面的准确性很差.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 脑卒中医学 脑卒中医学
背景情况:
- 许多急性缺血性中风 (AIS) 患者的发病时间不明,这使治疗决策和资格复杂化.
- 对于未知发病的AIS患者来说,先进的成像或从治疗中排除是常见的.
- 专注于内血管治疗 (EVT) 的MR CLEAN注册表提供了研究这一临床挑战的数据.
研究的目的:
- 调查AIS患者的临床放射学变量和开始到成像时间之间的关联.
- 确定非对比计算断层扫描 (NCCT) 和CT血管图 (CTA) 的发现是否可以预测AIS中的延迟成像.
- 评估这些关联的准确性,以预测晚期开始到成像窗口的准确性.
主要方法:
- 来自MR CLEAN注册表的4003名AIS患者的分析.
- 将患者分为早期 (≤4.5h; ≤6h) 和晚期 (>4.5h; >6h) 的时间窗口.
- 单变量,多变量逻辑回归和ROC曲线分析以评估关联和准确性.
主要成果:
- 下阿尔伯塔州中风计划早期CT评分 (ASPECTS) 和白内障病的存在与晚发到成像时间 (>4.5h和>6h) 有关.
- 较高的抵押分数 (中等和良好) 也与较晚开始到成像时间有显著的关联.
- 通过ROC曲线下的面积来测量的准确性,对于>4.5h和>6h的时间窗口 (0.63) 都很差.
结论:
- 在MR CLEAN注册表中的AIS患者中,降低ASPECT,白血病和更高的附带评分与延迟开始到成像时间相关.
- 这些临床放射学变量在预测AIS患者是否会进入晚期发病到成像时间窗口方面表现出有限的准确性.
- 可能需要进一步的研究,以改进AIS患者的预测模型,其发病时间尚不清楚.
相关概念视频
01:30Acute Coronary Syndrome III: Diagnostic Studies
23
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
23
01:19Imaging Studies VII: Vascular Imaging
55
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
55
01:28Imaging Studies for Cardiovascular System V: CT
66
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
66
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
23
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
23
01:21Imaging Studies for Cardiovascular System IV: CMRI
137
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
137