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改善炎症性肠道疾病患者的便样本采集:对两种calprotectin设备的比较评估

Giulia Pasi¹, Amale Antari², Damien Masson²

¹Institut des Maladies de l'Appareil Digestif (IMAD), Hépato-Gastro-Entérologie et Assistance Nutritionnelle, Inserm CIC 1413, Nantes Université, CHU Nantes, F-44000 Nantes, France.

Clinics and research in hepatology and gastroenterology

|August 4, 2025

概括

与标准容器相比,一个新的采样瓶显著提高了便calprotectin (FC) 检测在炎症性肠病 (IBD) 中的患者接受度. 这种以患者为中心的创新可以加强常规FC测试,以更好地管理IBD.

科学领域:

胃肠病学胃肠病学
临床诊断临床诊断临床诊断
生物标记分析生物标记分析

背景情况:

便calprotectin (FC) 是指导炎性肠病 (IBD) 治疗的关键非侵入性生物标志物.
患者对常规FC检测的遵守率低,主要是由于便收集的挑战,限制了其临床实用性.

研究的目的:

为了比较新型便取样瓶与常规容器在IBD患者中进行FC测试的可接受性和合规性.
评估以患者为中心的创新,以改善诊断测试的遵守性.

主要方法:

对156名IBD患者进行前性研究,随机分配到标准或新型采样设备.
通过定性和定量尺度评估可接受性;记录合规率.
专注于便采样程序,不包括点的护理测试满意度.

主要成果:

这种新型采样瓶在顺序尺度上显示出显著更高的患者可接受性 (OR2.69,p < 0.001).
在视觉模拟尺度上观察到可接受性的积极趋势,尽管在统计学上并不显著.
通过这两种抽样方法实现了高且可比的合规率 (80%).

结论:

采样瓶代表了在FC检测中收集便的更为患者友好的替代方案.
提高便收集的患者接受度可以提高常规FC测试的遵守率.
整合以患者为中心的创新对于优化IBD监测和管理至关重要.

关键词:

坚持的坚持坚持的坚持生物标志物生物标志物合规性合规性合规性克罗恩氏病是什么克罗恩氏病是什么性结肠炎是一种

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