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从内微生物群中获得的丁酸盐有助于骨髓瘤的肺转移

Jianing Yu1, Wuyan Lu2, Yang Chen3

  • 1The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266003, China.

Pharmacological research
|August 4, 2025
PubMed
概括

内微生物组的变化可以预测骨髓瘤转移. 微生物代谢物酸盐通过激活Wnt/β-catenin通路来促进癌症的扩散,从而提供了新的治疗点.

关键词:
生物标志物 生物标志物黄糖酸盐是什么 黄糖酸盐转移 转移 转移 转移微生物组是一个微生物组.骨质肉瘤骨质肉瘤是什么

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Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...