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通过使用原子层沉积制备的热稳定,一次性使用的狂犬病疫苗产生优异的免疫反应

Theodore Randolph1, Holly Coleman1, Amber M Rauch2

  • 1Department of Chemical and Biological Engineering, University of Colorado Boulder, CO 80303, USA.

Journal of pharmaceutical sciences
|August 4, 2025
PubMed
概括

本研究提出了一种新型,单剂量狂犬病病毒 (RABV) 疫苗,使用喷雾干燥和原子层沉积 (ALD). 新的疫苗配方具有耐热性,并且比传统疫苗引起的免疫反应要高得多.

关键词:
原子层沉积的原子层沉积.免疫性 免疫性 免疫性微粒微粒的使用方法喷雾干燥 喷雾干燥接种疫苗的交付时间.疫苗 疫苗是一种疫苗.

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Vaccines are among the most effective tools in preventive medicine, designed to prepare the immune system to recognize and combat infectious agents. By introducing antigens—substances that the immune system identifies as foreign—vaccines stimulate an adaptive immune response that leads to immunological memory. This immunological memory enables the body to mount a faster and more effective response upon future exposures to the actual pathogen.Vaccines can be categorized based on the...
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