相关实验视频
Updated: Sep 12, 2025

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
活跃结核病和多发性硬化症:治疗前查的重要性
Leizian de Souza Amorim1, Paloma Peter Travassos Zaidan1, Felipe Toscano Lins de Menezes1
1Universidade Federal de São Paulo, Escola Paulista de Medicina, Departamento de Neurologia e Neurocirurgia, São Paulo SP, Brazil.
结核病 (TB) 再激活是多发性硬化症 (MS) 患者服用疾病修饰药物 (DMD) 的风险. 对于开始DMD治疗的MS患者来说,早期结核病查至关重要,以防止疾病恶化.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 结核病 (TB) 在免疫功能低下的个体,包括患有多发性硬化症 (MS) 的人群中存在重新激活的风险.
- 用于MS的疾病修饰药物 (DMD) 可以进一步影响免疫功能,可能增加结核病风险.
- 需要明确的指导方针传染病查的MS患者开始DMDs.
研究的目的:
- 调查多发性硬化症患者的肺结核再激活的发生和影响,这些患者正在接受疾病修饰药物治疗.
- 突出这一患者群体中预防性肺结核查的重要性.
主要方法:
- 对2,036名多发性硬化症患者的回顾性病例系列分析.
- 包括6名被诊断患有结核病的患者,同时接受各种DMD (fingolimod,干扰素β1a,glatiramer乙酸盐,环胺).
主要成果:
- 两名患者在结核病治疗期间经历了MS残疾恶化.
- 在完成结核病治疗后,三名患者的残疾增加.
- 这项研究涉及一小群患有结核病的多发性硬化症患者,表明与DMD相关的潜在风险.
结论:
- 对于所有被考虑接受DMD治疗的MS患者来说,结核病查是必不可少的,特别是新的,高效的治疗方法.
- 制定基于证据的指导方针,用于MS患者的传染病查至关重要.
- 预防性感染风险管理对于优化多发性硬化症患者的治疗结果至关重要.
更多相关视频
03:47A Retrospective Study on Endoscopic Surgery for the Treatment of Paravertebral Abscess in Spinal Tuberculosis Patients
Published on: October 25, 2024
09:57System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
Published on: April 5, 2017
相关概念视频
Pulmonary Tuberculosis IV
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...
Pulmonary Tuberculosis V
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the...
Pulmonary Tuberculosis I
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...
Pulmonary Tuberculosis II
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...
Pulmonary Tuberculosis III
The first classification is based on the development of the disease, and it includes the following categories:
Transmission-based Precautions II: Airborne and Protective Environment
Airborne precautions:
Use airborne precautions when treating patients known or suspected to have diseases that spread through the air—for example, tuberculosis or measles. These organisms are present in smaller droplets expelled by an infected person and...