相关实验视频

Updated: Sep 12, 2025

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses
10:13

Tailoring In Vivo Cytotoxicity Assays to Study Immunodominance in Tumor-specific CD8+ T Cell Responses

Published on: May 6, 2019

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一个特定于CD4+ T淋巴细胞的TCR/GSDMD/IL-2轴促进抗瘤免疫力

Yihan Yao1, Lingling Wang1, Weiqin Jiang2

  • 1Institute of Immunology and Bone Marrow Transplantation Center and.

The Journal of clinical investigation
|August 4, 2025
PubMed
概括

加斯德明D (GSDMD) 蛋白对于CD4+ T细胞来说至关重要,通过诱导IL-2的产生来支持CD8+ T细胞抗瘤免疫力. 这一发现揭示了GSDMD在癌症免疫力中的新作用.

关键词:
信号传递的.癌症免疫疗法癌症免疫疗法免疫学 免疫学 免疫学在瘤学瘤学.在T细胞,T细胞.

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