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在基于瘤的分子分析过程中检测可能的生殖系变异.

Diana Jaber1, Jessica Zhang1, Lucy A Godley1,2

  • 1Department of Medicine, Northwestern Medicine, Chicago, Illinois, USA.

The Journal of clinical investigation
|August 4, 2025
PubMed
概括

下一代测序 (NGS) 瘤概况越来越多地检测出生殖线DNA的改变. 了解这些偶然发现对于准确的癌症风险评估和个性化治疗策略至关重要.

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Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
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