长期COVID的高压氧疗法:一个潜在的注册表
J van Berkel1, R C Lalieu2, D Joseph1
1Eurocept Clinics, Amersfoort/Rotterdam, The Netherlands.
高压氧气疗法 (HBOT) 对长期的COVID症状显示出潜在的益处,改善了许多患者的认知功能. 然而,一些人经历了症状恶化,需要在治疗期间仔细监测.
科学领域:
- 高压医学的高压医学.
- 后COVID条件 后COVID条件
- 患者的治疗结果.
背景情况:
- 对长期COVID症状的高压氧疗法 (HBOT) 的需求越来越大.
- 缺乏正式的指导方针和长期COVID中HBOT的报销.
- 需要更多关于患者特征和结果的数据.
研究的目的:
- 为了了解接受HBOT的长期COVID患者.
- 评估患者的特征和 (长期) 结果.
- 从一个潜在的注册表中报告3个月的结果.
主要方法:
- 接受HBOT的长期COVID患者的潜在注册.
- 在基线,治疗后,3个月和1年的随访期间收集患者报告的结果措施 (PROMs).
- 主要结局:SF-36精神和身体组件分数 (MCS/PCS);次要结局:EQ-5D,症状严重程度,工作能力.
主要成果:
- 56-63%的患者在3个月后在MCS/PCS中显示出临床相关的改善.
- 13-19%的患者在MCS/PCS中出现了临床相关的恶化.
- 认知领域的症状显示出最显著的改善.
结论:
- HBOT可能会对长期的COVID症状产生积极影响,特别是认知投诉.
- 对可能恶化的情况保持警至关重要.
- 需要进一步的研究来制定正式的指导方针和补偿.
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