基于GBD 2021的1990年至2021年的中国环境和家庭PM2.5的中风负担分析
Wanghong Su1, Chenran Zhang1, Huijuan Xi1
1School of Public Health, Health Science Center, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China.
Scientific reports
|August 4, 2025
概括
颗粒物 (PM2.5) 污染显著增加了中风负担,特别是在中国. 加强PM2.5控制措施对于公共卫生至关重要,特别是对于中年和老年人群.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 快速的城市化和经济增长导致PM2.5污染增加,这是一个重要的环境风险因素.
- 由于环境和家庭中的PM2.5暴露,尤其是像中国这样的发展中国家中风负担需要更多的关注.
- PM2.5是一种可修改的风险因素,与各种健康结果有关,包括心血管疾病.
研究的目的:
- 在1990-2021年期间,调查全球和中国的环境和家庭PM2.5暴露引起的中风亚型 (ICH,IS,SAH) 的疾病负担.
- 分析与PM2.5暴露相关的中风负担的趋势和特定年龄的模式.
- 根据PM2.5暴露水平预测未来的中风负担,并为公共卫生战略提供信息.
主要方法:
- 利用了来自全球疾病负担 (GBD) 数据库 (1990-2021) 的数据.
- 雇员联合点回归计算疾病负担率的年平均百分比变化 (AAPC).
- 应用贝叶斯年龄周期队列 (BAPC) 模型用于疾病负担预测.
主要成果:
- 脑内出血 (ICH) 和缺血性中风 (IS) 是主要的中风亚型,有助于总负担归因于PM2.5.5.
- 在全球和中国,中风负担随着1990年至2021年间环境PM2.5暴露的增加而增加.
- 在中国,ICH和IS的年龄标准化率在55-59岁年龄组达到顶峰,预测表明未来25年负担将翻一番.
结论:
- 与PM2.5相关的中风的增加和稳定负担凸显了加强控制措施的迫切需要.
- 政府的共同努力对于减轻PM2.5暴露至关重要,特别是在中国的中年和老年人等弱势群体.
- 解决环境和家庭PM2.5对于减少全球中风负担至关重要.
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