自闭症成年人中使用心理药物的预测因素
Océane Mahé1,2, Shasha Morel-Kohlmeyer3,4,5, Frédéric Briend3,5
1EXcellence Center in Autism and Neurodevelopmental Disorders - Tours ExAC-T, Tours, France. O.mahe@chu-tours.fr.
Journal of autism and developmental disorders
|August 5, 2025
概括
心理药物治疗在自闭症成年人中很常见,特别是那些有智力和发育障碍 (IDD) 的人. 同时出现的疾病,如和情绪障碍,增加了对多种药物的需求.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
背景情况:
- 自闭症谱系障碍 (ASD) 影响社会沟通和行为.
- 目前没有一种心理药物治疗可以解决自闭症的核心症状.
- 了解自闭症成年人的药物使用对于有效的护理至关重要.
研究的目的:
- 在自闭症成年人中识别心理药物使用的预测因素.
- 检查与药物治疗相关的人口,诊断和功能因素.
- 为了区分单独的ASD与ASD与智力和发育障碍 (IDD) 的药物治疗模式.
主要方法:
- 来自法国自闭症资源中心的391个成年人记录的回顾性研究.
- 参与者分为自闭症谱系障碍 (ASD),智力和发育障碍 (IDD) 和ASD+IDD组合组.
- 多项逻辑回归分析以确定预测心理药物单疗法和多疗法的因素.
主要成果:
- 44.9%的IDD自闭症成年人接受了多种精神药物治疗,而没有IDD的成年人则是17%.
- 多疗法的预测因素包括老年,和外部化行为.
- 焦虑和情绪障碍预测单疗法和多疗法;IDD是多疗法的重要因素.
结论:
- 同时发生的IDD,年龄较大,,焦虑,情绪障碍和外部化行为预测自闭症成年人使用心理药物.
- 在患有IDD的自闭症成年人中,多药性治疗的更高率令人担忧.
- 对这一群体需要改进心理教育支持和有针对性的治疗.
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