相关实验视频

Updated: Sep 12, 2025

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Machine Learning Algorithms for Early Detection of Bone Metastases in an Experimental Rat Model

Published on: August 16, 2020

开放式放射学:标准化数据集的集合和可复制的放射学机器学习管道的技术协议

Khashayar Namdar^1,2,3,4, Matthias W Wagner^1,2,5,6, Birgit B Ertl-Wagner^1,2,5

¹Department of Diagnostic & Interventional Radiology, The Hospital for Sick Children (SickKids), Toronto, ON, Canada.

BMC medical imaging

|August 5, 2025

概括

放射学可重现性受到特征提取变异性的挑战. 瘤子区域和成像序列显著影响模型性能,一些完美的结果被证明是不可重现的.

科学领域:

机器学习在医学成像中的应用.
放射学及其应用.
科学研究中的可复制性

背景情况:

放射学是医学成像中的机器学习的一个关键组成部分,在可复制性和可访问性方面面临重大挑战.
研究放射学特征提取对结果可重现性的影响对于临床采用至关重要.

研究的目的:

引入开放式放射学,一个新的放射学数据集和一个全面的管道.
调查放射学特征提取对结果可重复性的影响,使用拟议的技术协议.

主要方法:

来自开源源 (BraTS 2020,BraTS 2023,TCIA) 的大型放射学数据集,用于质瘤和非小细胞肺癌研究.
利用BraTS 2020 MRI数据集创建了288个放射学数据集,通过不同的MRI序列,容器宽度,正常化方法和瘤子区域来创建.
在每个数据集上执行了100倍的交叉验证与随机森林分类器,以通过接收器操作特征曲线 (AUROC) 下的区域评估可重复性.

主要成果:

瘤子区域和成像序列是影响模型性能的重要因素,与 bin 宽度和图像正常化不同.
T1对比增强序列和瘤亚区域的特定组合产生了最高的平均测试AUROC (0.951).
虽然一些设置实现了完美的AUROC分数 (1),但这些结果被发现是不可重现的.

结论:

放射学管道的变化,特别是关于瘤亚区域选择的变化,可以显著影响结果.
在放射学研究中,表面上的完美表现可能来自不可重现的因素,这凸显了对强大的方法学的需求.

关键词:

脑癌脑癌是一种脑癌.数据集数据集数据集这是开源的,开源的.无线电学 (Radiomics) 是一种无线电学.可复制性可复制性

更多相关视频

Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics

Guidelines and Experience Using Imaging Biomarker Explorer IBEX for Radiomics

Published on: January 8, 2018

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases

Published on: May 17, 2019

相关概念视频

Radiological Investigation I: X-ray and CT

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...

Positron Emission Tomography

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...