风湿病患者对COVID-19疫苗的看法
Liz Romero-Bogado1, Martina Steiner1, Cristina Andreu-Vázquez2
1Rheumatology Section, Hospital Universitario Infanta Sofía, FIIB HUIS HHEN, Universidad Europea de Madrid, Madrid, Spain.
Medicine
|August 5, 2025
概括
接种COVID-19疫苗改善了风湿病患者的结果,大多数人感到受到保护. 然而,COVID-19的发病率和严重程度在各个患者群体中仍然相似,这凸显了持续预防感染的必要性.
科学领域:
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
- 疫苗学 疫苗学 疫苗学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 疫苗的广泛采用已经显著改变了感染动态.
- 患有风湿性疾病的患者经历了改善的结果,主要是由于免疫接种.
研究的目的:
- 评估COVID-19疫苗的感知和保护.
- 为了比较COVID-19发病率和疫苗接种前和后的严重程度,在风湿病患者中.
- 在不同类型的患者和免疫抑制治疗中分析这些因素.
主要方法:
- 一个观察性,描述性-分析性,两面性和横截面性研究.
- 对407名患有免疫媒介炎症疾病 (IMID) 和非自身免疫肌肉骨疾病的患者进行了问卷调查.
- 所有参与者都至少接种了两剂COVID-19疫苗.
主要成果:
- 大多数患者 (78.1%) 感觉受到COVID-19疫苗的保护,看法因患者类型而异.
- 接受常规合成或生物药物的IMID患者报告的感知保护比非自身免疫患者更高.
- 在患者组或治疗类型之间没有观察到COVID-19发病率或严重性的显著差异.
结论:
- 在IMID患者中,免疫抑制治疗与更高的感知疫苗保护有关.
- 尽管感知到保护,但COVID-19的发病率和严重程度在IMID和非自身免疫患者中是可比的.
- 加强了感染控制的重要性,并监测了类风湿病患者的疫苗接种策略.
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