2型糖尿病中的水平和相关因素:一个横截面研究
Kamil Konur1, Hatice Beyazal Polat1, Erol Karavar1
1Recep Tayyip Erdoğan University, Faculty of Medicine, Department of İnternal Medicine, Rize, Türkiye.
Endocrine, metabolic & immune disorders drug targets
|August 5, 2025
概括
在2型糖尿病患者中血清含量较低,血糖控制较差,特别是在女性中. 虽然不是直接的预测因素,但水平与高血压和心力衰竭相关,这表明它在糖尿病管理中发挥了作用.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 临床化学 临床化学
背景情况:
- 2型糖尿病 (T2DM) 是一种代谢障碍,经常与血清的变化有关.
- 了解在T2DM中的作用对于患者管理至关重要.
研究的目的:
- 研究2型糖尿病患者血清度和血糖控制之间的关系.
- 探索与并发症和药物使用的关联.
主要方法:
- 502名T2DM患者的回顾性横截面分析.
- 通过HbA1c对血糖控制的评估.
- 包括后勤回归和ROC曲线分析在内的统计分析.
主要成果:
- 在血糖控制不良的患者中观察到较低的血清度.
- 女性,特别是绝经后妇女的含量明显较低.
- 发现与高血压,性别和甲福明和因达帕米德等药物的关联;与充血性心力衰竭 (CHF) 的反向关联.
结论:
- 仅仅血清水平并不是T2DM中血糖控制的可靠预测指标.
- 与心血管梗塞,高血压 (HT),性别和药物的关联凸显了它在T2DM中的复杂作用.
- 监测可能有助于识别有风险的患者;需要进一步的前性研究.
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
2.9K
Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
2.9K
Diabetes Mellitus: Overview and Type I Subtype
3.2K
Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
3.2K
Carbohydrate Metabolism
11.7K
Carbohydrates are polymers composed of molecules containing atoms of carbon, hydrogen and oxygen. One gram of carbohydrate can provide four kilo-calories of energy, which makes it the most efficient instant energy source.
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
11.7K
Diabetes: Symptoms, Diagnosis, and Complications
694
For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
694
Pathophysiology of Diabetes
1.2K
Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia. The four categories of diabetes are type 1 diabetes, type 2 diabetes, other specific types of diabetes, and gestational diabetes.
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
Type 1 diabetes is characterized by autoimmune-mediated destruction of pancreatic β cells, with environmental factors potentially triggering this process in genetically susceptible individuals. Despite many not having a family history, certain genes increase susceptibility,...
1.2K
Diabetes: Management and Pharmacotherapy
386
The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
386


