副本数量 变异形状 结构性基因组多样性 与野生番茄的生态适应相关 番茄 Solanum chilense
Kai Wei1,2, Remco Stam3, Aurélien Tellier2
1Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830049, China.
Molecular biology and evolution
|August 5, 2025
概括
复制数变异 (CNV) 驱动植物的适应. 在野生番茄 (Solanum chilense) 中,压力反应基因中的CNV揭示了与气候相关的进化趋势,有助于息地殖民.
科学领域:
- 植物基因组学 植物基因组学
- 进化生物学是进化的生物学.
- 人口遗传学 人口遗传学
背景情况:
- 复制数变异 (CNV) 显著影响植物遗传多样性和适应性.
- 了解野生亲属中的CNV对于改善作物至关重要.
- 野生番茄物种适应性中CNVs的作用仍然在很大程度上未被探索.
研究的目的:
- 在野生番茄物种Solanum chilense中描述CNV景观.
- 在人口层面上通过CNVs识别与适应相关的基因.
- 调查S. chilense.中CNVs的进化动态和环境关联.
主要方法:
- 来自7个种群的35个S. chilense个体的全基因组短读测序.
- 识别和分析副本数量变化 (删除和重复).
- 集成CNV数据与单核酸多态 (SNP) 分析和环境变量.
主要成果:
- 在S. chilense.中发现了212,207个CNV (160,926个删除,51,281个重复).
- 在来自压力息地的人群中观察到更高的CNV频率.
- 鉴定了3539个候选基因与不同的CNV配置文件,与非生物应激反应和开花时间相关.
结论:
- 在S. chilense中的CNV反映了历史的人口统计事件和最近的殖民.
- 基因拷贝数的变化与适应不同息地和气候变量有关.
- 自然选择很可能在压力反应基因中塑造了CNV模式,促进了适应和范围的扩张.
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