相关实验视频

Updated: Sep 12, 2025

An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme
07:45

An Explant Assay for Assessing Cellular Behavior of the Cranial Mesenchyme

Published on: January 20, 2013

9.9K

在β-catenin介导的表面外皮分化中,EMG1与GRHL3合作,以调节神经管闭合

Chiharu Kimura-Yoshida1, Kyoko Mochida1, Chihiro Matsuno1

  • 1Department of Molecular Embryology, Research Institute, Osaka Women's and Children's Hospital, Osaka Prefectural Hospital Organization, 840, Murodo-cho, Izumi, Osaka 594-1101, Japan.

Development (Cambridge, England)
|August 5, 2025
PubMed
概括

对于线粒生长至关重要的1 (EMG1) 蛋白与粒头样转录因子3 (GRHL3) 相互作用,调节胚胎发育. 这种相互作用对于预防神经管缺陷和理解遗传疾病,如脊柱裂变,至关重要.

关键词:
波恩康拉迪综合征 波恩康拉迪综合征规范的Wnt/β-catenin可以使用.皮肤上分化的表皮分化.人类 人类 人类 人类 人类鼠标 鼠标是一个鼠标.神经发射神经系统的形成.帕拉托基尼斯 (Palatogenesis) 是一个古老的发育过程.范德伍德综合症 2 范德伍德综合症

更多相关视频

Author Spotlight: Non-Contact Measurement of Tissue Mechanics in Live Chick Embryos Using Brillouin Microscopy05:51

Author Spotlight: Non-Contact Measurement of Tissue Mechanics in Live Chick Embryos Using Brillouin Microscopy

Published on: November 10, 2023

840
Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression11:48

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression

Published on: January 17, 2016

9.0K

相关概念视频

Catenins01:23

Catenins

Catenins are characterized by multiple binding domains and dynamic structures that allow them to function as linker proteins in cell junction complexes. All catenins, except α-catenin, contain a characteristic protein sequence called the armadillo repeat and are therefore also called armadillo proteins.
Catenins in Cell Junctions
Catenins bind to cell adhesion molecules such as cadherins and link them to different cytoskeletal proteins depending on the type of cell junction. At the...
2.4K
Cadherins in Tissue Organization01:19

Cadherins in Tissue Organization

The cadherins are a superfamily of cell adhesion molecules comprising over 180 variants, with specific tissues expressing a particular combination of cadherin types. Cadherins generally exhibit homophilic binding; i.e., cadherins on one cell bind to cadherins of the same or closely related type on another cell. Thus, cells of the same type have a specific affinity to bind to each other and sort themselves into clusters to form tissues.
Cell Sorting During Development
Cell sorting plays an...
3.1K
Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...
42.6K
Non-Canonical Wnt Signaling Pathways01:41

Non-Canonical Wnt Signaling Pathways

Wnt is a zygotic effect gene that is expressed during very early embryonic development. It regulates various processes in animals starting from early development through the adult stage, such as organogenesis in the embryo and maintenance of neuronal and blood stem cells. Wnt proteins can induce a wide variety of intracellular pathways depending upon the specific abilities of different Wnt ligands to form a complex with shared and cognate receptors in the presence of different co-receptors. The...
7.4K