减少卵巢储备的电针治疗:随机,安慰剂控制试验的协议
Han Tang1,2, Jia-Xuan Wang1, Shi-Zhong Zheng1
1Department of Acupuncture, Shenzhen Hospital of Shanghai University of Traditional Chinese Medicine, Shenzhen, Guangdong, People's Republic of China.
Journal of multidisciplinary healthcare
|August 5, 2025
概括
电针可以改善女性的生育能力减少卵巢储备 (DOR). 这项随机试验调查了它对卵巢标志物和怀孕结果的影响,提供了潜在的新治疗选择.
科学领域:
- 生殖医学 生殖医学
- 传统中国医药 传统中国医药
- 临床试验 临床试验
背景情况:
- 卵巢储备减少 (DOR) 显著影响生育年龄妇女的生育能力.
- 目前对DOR针的证据是不确定的,需要进一步严格调查.
- 电针 (EA) 被探索为潜在的治疗干预对DOR.
研究的目的:
- 评估电针 (EA) 在改善DOR妇女的卵巢储备指标方面的有效性.
- 评估EA对主要生殖结果的影响,包括怀孕和活产率.
- 为了确定EA是否可以显著提高被诊断为DOR的妇女的生育潜力.
主要方法:
- 一个为期12周的随机,盲目,安慰剂控制试验,涉及112名参与者 (20-48岁) 在中国深.
- 参与者被分配到电针 (EA) 或假电针 (SA) 组 (1:1比),每周接受3次会议.
- 主要结局:毛囊数量的变化;次要结局:激素水平,情绪和妊娠率.
主要成果:
- 预计主要结局指标的毛囊平均增加为2.2个.
- 评估基底激素水平的变化,反米勒尔激素和心理健康.
- 计划对怀孕结果,年龄组和排卵诱导参数进行子组分析.
结论:
- 这项研究协议已获得伦理认可和注册 (ISRCTN:69623204).
- 结果将通过开放式出版物和会议传播.
- 这些发现旨在为临床实践提供有关卵巢储备减少的电针的信息.
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