在中等风险国家进行胃癌内镜查 - - 双中心试点项目
M B Mourato1,2, N Pratas2, A Branco Pereira2
1NOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, LA-REAL, CCAL, NOVA University Lisbon, Lisbon, Portugal.
Helicobacter
|August 5, 2025
概括
与结直肠癌查相结合的机会性上部内镜在葡萄牙是可行的,在诊断上有价值的. 这种方法有效地识别了癌前疾病和恶性瘤,支持结构化查策略.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 胃癌是一个全球性的健康问题,在西方国家经常被诊断为晚期.
- 葡萄牙缺乏国家胃癌查计划,尽管有证据表明它在中等风险地区有利.
- 这项研究与结直肠癌查一起研究机会性上部内镜.
研究的目的:
- 评估机会性上部内镜的可行性和遵守性.
- 评估上部内镜在与结直肠癌查相结合时的诊断产量.
- 为葡萄牙实施结构化查策略提供证据.
主要方法:
- 在两个葡萄牙内镜单位进行了观察性回顾性研究.
- 预定接受查结肠镜检查的50-74岁的个人被邀请参加上部内镜检查.
- 收集和分析了人口统计,内镜检查结果和组织学数据.
主要成果:
- 在受邀个人中,上部内镜的接受率高 (94.8%).
- 感染Helicobacter pylori (30.8%),慢性缩性胃炎 (36.9%) 和肠道代谢 (10.1%) 的患病率.
- 检测到的瘤病变包括1.9%的恶性瘤 (胃腺癌,GIST) 和0.5%的低度内皮瘤;发现了29.2%的癌前病变和3.4%的侵袭性结肠直肠癌病变.
结论:
- 与结直肠癌查相结合的机会主义上部内镜是可行的,并且在中等风险的西方人口中得到了很好的接受.
- 前癌症和恶性瘤的高检测率强调了结构化查计划的必要性.
- 研究结果支持在类似的医疗机构更广泛地实施综合查策略.
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