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Updated: Sep 12, 2025

Dual CRISPR-Interference Strategy for Targeting Synthetic Lethal Interactions Between Non-Coding RNAs in Cancer Cells
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倒置仿真RNAi分子在KRAS驱动的癌症中协同准MYC和KRAS

Yogitha S Chareddy1, Hayden P Huggins2, Snehasudha S Sahoo3

  • 1Curriculum in Genetics and Molecular Biology, University of North Carolina at Chapel Hill, Chapel Hill, United States of America.

The Journal of clinical investigation
|August 5, 2025
PubMed
概括

一种新型的仿真RNAi分子同时准KRAS和MYC瘤基因,克服癌症抵抗力. 这种双沉默策略显示了有效性和瘤减少的显著改善.

关键词:
药物治疗是药物治疗.肺癌是一种肺癌.瘤基因是一种瘤基因.在瘤学瘤学.治疗方法 治疗方法

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