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Updated: Sep 12, 2025

Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates
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Deacetylation Assays to Unravel the Interplay between Sirtuins SIRT2 and Specific Protein-substrates

Published on: February 27, 2016

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蛋白脱乙酶SIRT2对适应性β细胞增殖进行代谢控制

Matthew Wortham1, Bastian Ramms1, Chun Zeng1

  • 1Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diab, UCSD, La Jolla, United States of America.

The Journal of clinical investigation
|August 5, 2025
PubMed
概括

科学家们发现,在胰腺β细胞中抑制Sirtuin 2 (SIRT2) 在高血糖期间促进受控的β细胞增殖,提供潜在的糖尿病治疗. 这种方法可以保持反控制,防止细胞过度生长.

关键词:
贝塔细胞 贝塔细胞 贝塔细胞糖尿病 糖尿病 糖尿病内分泌学 在内分泌学.代谢过程中的代谢.线粒体中的线粒体.

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