携带肠道衍生细菌DNA的亲炎性巨细胞驱动脊髓关节炎的自身免疫性关节炎

Benjamin Cai1, Rabina Giri2, Amy J Cameron1

  • 1Frazer Institute, The University of Queensland, Brisbane, Australia.

JCI insight
|August 5, 2025
PubMed
概括

脊椎关节炎涉及肠道细菌,在遗传敏感的个体中触发免疫反应. 这项研究揭示了肠道细菌和免疫细胞如何促进小鼠自身免疫性疾病的发展,为人类牛皮关节炎提供了洞察力.

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