西诺氨酸化物通过抑制Th1细胞诱导的M1巨细胞烧灭症来缓解自身免疫性心肌炎

Zhenhao Zhang1, Yulong Xiong1, Shangyu Liu1

  • 1Department of Cardiology, Fuwai Hospital, State Key Laboratory of Cardiovascular Diseases, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 167A Beilishi Road, Xi Cheng District, Beijing 100037, PR China.

概括

辅助T1 (Th1) 细胞通过促进巨细胞的灭,驱动心肌炎. 西诺氨酸化物抑制Th1细胞活化和氨酸代谢,为心肌炎提供了潜在的治疗方法.

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