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与口腔癌患者术后口腔功能障碍相关的因素:一个结构方程建模研究
Yuhei Matsuda1, Masako Fujioka-Kobayashi1, Hiroto Tatsumi2
1Department of Oral and Maxillofacial Surgery, Shimane University Faculty of Medicine, Izumo, Japan.
Oral oncology
|August 5, 2025
概括
口腔癌治疗显著恶化了口腔功能,如舌头压力和能力. 这些变化会对患者的口腔健康相关生活质量产生负面影响.
科学领域:
- 口腔和牙面部外科手术
- 在瘤学瘤学.
- 康复医学 康复医学 康复医学
背景情况:
- 口腔状细胞癌 (OSCC) 的治疗往往导致口腔功能障碍.
- 治疗后测量口腔功能的现有方法缺乏全面的验证.
- 这项研究解决了对口腔功能变化及其对OSCC治疗后生活质量影响的标准化评估的需求.
研究的目的:
- 为了研究OSCC治疗后口腔功能的变化.
- 确定与这些患者的口腔健康相关生活质量 (OHRQoL) 相关的因素.
主要方法:
- 进行了一项前性观察性队列研究.
- 包括112名患有OSCC的患者.
- 治疗前后评估了口腔功能,OHRQoL (使用GOHAI) 和一般健康状况.
主要成果:
- 治疗OSCC显著损害了微生物数量,闭塞力,舌头压力,功能和吞能力 (EAT-10).
- GOHAI分数与舌头压力和EAT-10分数显著相关.
- 患者背景和术后口腔功能与OHRQoL相关.
结论:
- 治疗OSCC会对关键的口腔功能产生负面影响,包括闭塞力,舌头压力,功能和吞.
- 舌头压力降低和吞能力受损与口腔健康相关的生活质量降低有关.
- 了解这些功能缺陷对于改善患者治疗后的结果和生活质量至关重要.
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