肥胖对甲状腺切除术结果的临床影响:系统性审查和元分析
Ahmed Ghani1, Lamees M Al Darwashi2, May Y Hajeir2
1School of Medicine, University College Dublin, Dublin, Ireland. Electronic address: https://twitter.com/UCDMedicine.
Surgery
|August 5, 2025
概括
肥胖增加了甲状腺手术期间血液瘤,神经损伤和伤口问题的风险,尽管甲状腺功能低下的几率较低. 需要进一步的研究来确保患者的安全.
科学领域:
- 内分泌学 在内分泌学.
- 手术瘤学手术瘤学
- 公共卫生 公共卫生
背景情况:
- 全球肥胖率的上升需要了解它们对手术结果的影响.
- 甲状腺切除术是一种常见的手术,肥胖个体的患者安全需要仔细评估.
研究的目的:
- 进行一项元分析,评估甲状腺切除术在肥胖患者中的安全性.
- 在肥胖人口中确定与甲状腺手术相关的特定风险和益处.
主要方法:
- 在主要数据库 (PubMed,Embase,Cochrane等) 中进行了全面的文献搜索. 在2025年2月之前.
- 按照PRISMA指南进行的系统审查和元分析,并可能在PROSPERO.上注册.
主要成果:
- 对10项研究的分析 (108,153名患者) 显示,肥胖患者 (22%) 患有重复性喉神经损伤,血瘤和伤口并发症的风险更高.
- 相反,肥胖的患者表现出较低的偏偏甲状腺功能障碍率.
- 在肥胖和非肥胖组之间,在手术时间或住院时间方面没有发现显著差异.
结论:
- 肥胖与特定甲状腺切除术并发症的风险增加有关,尽管甲状腺功能低下的风险较低.
- 建议进行进一步的研究,以探索分层体质指数 (BMI) 分类,并制定策略,以减轻接受甲状腺切除术的肥胖患者的手术风险.
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