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Updated: Sep 12, 2025

Antimicrobial Peptides Produced by Selective Pressure Incorporation of Non-canonical Amino Acids
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Published on: May 4, 2018

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具有高治疗指数的α-螺旋型抗微生物,具有对抗多药耐药细菌的重复子单元结构

Jingying Zhang1, Anqi Chu1, Ping Yang1

  • 1Institute of Pharmaceutics, School of Pharmacy, Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences, and Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066, Lanzhou University, Lanzhou, 730000, PR China.

European journal of medicinal chemistry
|August 5, 2025
PubMed
概括

研究人员设计了新型抗微生物 (AMP) 来对抗抗生素耐药性. 最佳 (27) 在感染模型中显示出对抗性细菌的广泛活性,具有低毒性和有效性.

关键词:
抗生物膜活动活性.低阻力发展的发展.耐多药性 (MDR) 细菌感染重复的子单位是重复的子单位.α-螺旋式抗微生物 (AMP) 是一种抗微生物.

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