Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Classification of Leukocytes01:30

Classification of Leukocytes

2.7K
Leukocytes are classified into two groups based on the presence or absence of cytoplasmic granules. Granular leukocytes, which contain granules, belong to the myeloid lineage and are divided into three subtypes: neutrophils, eosinophils, and basophils. These cells are roughly spherical and characterized by the granules in their cytoplasm.
Neutrophils are the most abundant type of granular leukocytes, comprising 50-70% of all leukocytes. They feature small, evenly distributed granules and a...
2.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Depth of neutrophil mobilization stratifies survival in ST-elevation myocardial infarction.

Nature cardiovascular research·2026
Same author

A gene signature derived from leukemia associated macrophages provides a compelling risk stratification for human AML patients.

Biomarker research·2026
Same author

Distinct immune landscapes characterize highly versus minimally invasive brain metastases.

JCI insight·2026
Same author

CCR2<sup>+</sup> Neutrophils Exhibit a Proinflammatory Phenotype and Contribute to Plaque Vulnerability.

Arteriosclerosis, thrombosis, and vascular biology·2026
Same author

Author Correction: The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis.

Nature·2026
Same author

Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense.

Science immunology·2026
Same journal

Targeting cholesterol esterification sensitizes liver cancer to CD8<sup>+</sup> T cell attack by impairing metabolic and redox resilience.

Immunity·2026
Same journal

Brain endothelial cells orchestrate a neuroprotective antiviral state in the CNS in response to peripheral viral pattern sensing.

Immunity·2026
Same journal

Extracellular ATP-P2RY2 signaling drives intratumoral prostaglandin E2 accumulation and adaptive resistance to immunotherapy in solid tumors.

Immunity·2026
Same journal

B cell-derived type I interferon sustains T cell functionality upon strong TCR stimulation during chronic infection.

Immunity·2026
Same journal

Lactate binds and inhibits the innate immune sensor STING to promote tumor immune evasion.

Immunity·2026
Same journal

Antibody binding geometry and affinity control inhibitory hFcγRIIB receptor signaling.

Immunity·2026
查看所有相关文章

相关实验视频

Updated: Sep 12, 2025

ATAC-Seq Library Preparation of Murine Bone Marrow-Derived Neutrophils
09:44

ATAC-Seq Library Preparation of Murine Bone Marrow-Derived Neutrophils

Published on: January 3, 2025

618

从复杂性到共识:中性粒细胞分类的路线图

Lai Guan Ng1, Ivan Ballesteros2, Marco A Cassatella3

  • 1School of Medicine, Westlake University, Hangzhou, Zhejiang, China; Shanghai Immune Therapy Institute, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Immunity
|August 5, 2025
PubMed
概括
此摘要是机器生成的。

中性粒细胞是多样化的免疫细胞,不是统一的. 一个新的框架标准化了根据成熟,位置和功能对中性粒细胞亚种群的分类,以便更清晰的研究和治疗.

关键词:
在MDSCs中.坦斯 (TANs) 是一个达成共识声明 达成共识声明中性粒细胞的适应.中性粒细胞分类框架中性恋异质性的异质性中性粒细胞成熟的过程

更多相关视频

Isolation and Characterization of Neutrophils with Anti-Tumor Properties
10:15

Isolation and Characterization of Neutrophils with Anti-Tumor Properties

Published on: June 19, 2015

25.0K
Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol
12:27

Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol

Published on: February 9, 2024

3.1K

相关实验视频

Last Updated: Sep 12, 2025

ATAC-Seq Library Preparation of Murine Bone Marrow-Derived Neutrophils
09:44

ATAC-Seq Library Preparation of Murine Bone Marrow-Derived Neutrophils

Published on: January 3, 2025

618
Isolation and Characterization of Neutrophils with Anti-Tumor Properties
10:15

Isolation and Characterization of Neutrophils with Anti-Tumor Properties

Published on: June 19, 2015

25.0K
Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol
12:27

Author Spotlight: Balancing Speed, Cost, and Accuracy in Neutrophil Function Assessment with NeutroFun Screen Protocol

Published on: February 9, 2024

3.1K

科学领域:

  • 免疫学 免疫学 免疫学
  • 细胞生物学 细胞生物学
  • 血液学 血液学 血液学

背景情况:

  • 中性粒细胞曾经被认为是一种统一的免疫细胞类型.
  • 最近的研究表明,中性粒细胞在表型和功能方面具有显著的异质性.
  • 现有的分类方法不一致,导致研究结果模两可.

研究的目的:

  • 提出一个标准化的框架来分类中性粒细胞异质性.
  • 将成熟,组织局部化和功能适应整合到一个统一的系统中.
  • 改善沟通,加速中性粒细胞生物学和治疗开发方面的发现.

主要方法:

  • 为中性粒细胞亚种群开发一种新的分类框架.
  • 整合多原子数据和先进的成像技术 (隐含).
  • 对现有文献进行比较分析,以确定分类缺口.

主要成果:

  • 一个拟议的框架根据成熟阶段,组织部位和功能专业化对中性粒细胞进行分类.
  • 该框架旨在解决当前中性粒细胞亚种群描述中的模两可.
  • 标准化有助于在不同研究和疾病背景下进行比较.

结论:

  • 一个标准化的系统对于理解中性粒细胞异质性至关重要.
  • 这一框架将协调研究,改善跨学科沟通,并指导治疗策略.
  • 这种系统的采用将促进中性粒细胞生物学和有针对性的治疗开发.