心脏代谢指数与阻塞性睡眠呼吸暂停的自我报告症状之间的关联:一个横截面研究
Mingyue Cui1, Xianchao Xiao1, Xue Zhao1
1Department of Endocrinology and Metabolism, The First Hospital of Jilin University, 71 Xinmin Street, Chaoyang District, Changchun, 130021, China.
Scientific reports
|August 5, 2025
概括
心脏代谢指数 (CMI) 是内脏脂肪的指标,与阻塞性睡眠呼吸暂停 (OSA) 有显著的关联. 这一发现表明CMI可能有助于预测成年人OSA风险.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征是代谢综合征的一种.
- 睡眠医学 睡眠医学
背景情况:
- 内脏脂肪与代谢功能障碍有关.
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍的睡眠障碍.
- 内脏脂肪指标和OSA之间的关联需要进一步调查.
研究的目的:
- 调查心脏代谢指数 (CMI) 和阻塞性睡眠呼吸暂停 (OSA) 之间的关系.
- 评估CMI对OSA在一个大规模,具有全国代表性的成年人群中的预测价值.
主要方法:
- 使用国家健康和营养检查调查 (NHANES) 数据 (2005-2008,2015-2018) 进行的横截面研究.
- 权重后勤回归和受限制的立方线分析了CMI和OSA的关联.
- 接收器操作特征 (ROC) 曲线评估了CMI对OSA的预测性能.
主要成果:
- 在完全调整的模型中,在较高的CMI和增加的OSA几率 (OR=1.75,95%CI 1.46-2.10) 之间发现了显著的关联.
- 对于年龄,性别,BMI或种族,没有观察到显著的相互作用效应.
- 预测OSA的CMI曲线下的面积 (AUC) 为0.605,表示预测值.
结论:
- 心脏代谢指数 (CMI) 独立地与美国成年人的阻塞性睡眠呼吸暂停 (OSA) 相关.
- 在OSA风险评估中,CMI显示出作为一种新型预测因素的潜力.
- 这些发现为管理患有OSA风险的个体提供了新的见解.
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