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Updated: Sep 12, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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东部马类脑炎病毒E2葡萄糖蛋白协调甲酸和蛋白质受体依赖感染的三个带正电荷的结合点

Maria D H Alcorn1,2, Chengqun Sun2, Theron C Gilliland2

  • 1Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.

Nature communications
|August 5, 2025
PubMed
概括

东部马脑炎病毒 (EEEV) 在其E2糖蛋白上使用多个位点来结合硫酸 (HS) 和蛋白质受体. 这些相互作用对于病毒感染性,疾病和蚊子传播至关重要.

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