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Updated: Jun 18, 2026

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卵巢清细胞癌在单细胞分辨率上的上皮特征

Qinhao Guo1,2, Xia Chen3,4, Rui Bi2,5

  • 1Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Fudan University, Shanghai, China.

Communications biology
|August 6, 2025
PubMed
概括

这项研究揭示了驱动卵巢清细胞癌 (OCCC) 发病和复发的关键转录因子 (TF). 识别这些TF为这种侵袭性卵巢癌提供了新的治疗点.

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Classification of Epithelial Tissues: Overview01:22

Classification of Epithelial Tissues: Overview

Epithelial tissues are classified according to the shape of the cells and the number of cell layers formed. Cell shapes can be squamous (flattened and thin), cuboidal (square-like, as wide as it is tall), or columnar (rectangular, taller than it is wide). Additionally, the nucleus shape helps identify the type of epithelial cells. Squamous cells have flattened disc-shaped nuclei, cuboidal cells have spherical nuclei, and columnar cells have elongated nuclei.
Based on the number of cell layers,...
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Classification of Epithelial Tissues: Simple Epithelium

Simple epithelium consists of a single layer of cells that lines body cavities and blood vessels. The shape of the cells in the epithelium reflects the function of the tissue. Cells in simple squamous epithelium appear as thin scales with flat, elliptical nuclei that mirror the form of the cell.
Because of the thinness of the cells, simple squamous epithelium is present where the rapid passage of chemical compounds is observed. For example, the endothelium that lines the capillaries and vessels...