在68Ga-FAPI PET/CT上模仿恶性瘤的良性十二指腺瘤
Xuezhi Lin1,2,3, Lu Zhang1,2,3, Guojian Zhang2,3
1The First Clinical Medical College of Inner Mongolia Medical University, Hohhot, Inner Mongolia, People's Republic of China.
Clinical nuclear medicine
|August 6, 2025
概括
这项案例研究表明,良性十二指肠瘤可以在PET/CT扫描上呈现为恶性病变. 对-68纤维细胞激活蛋白抑制剂PET/CT的强度FAPI吸收可能会模仿癌症,需要进行基因病理学确认.
科学领域:
- 在瘤学瘤学.
- 放射学 放射学是一门学科.
- 胃肠病学 胃肠病学
背景情况:
- 十二指腺瘤是一种罕见的良性瘤.
- 阳位子发射断层扫描/计算机断层扫描 (PET/CT) 对于癌症的分期和诊断至关重要.
- 纤维细胞激活蛋白抑制剂 (FAPI) PET/CT是一种用于各种癌症的新型成像技术.
研究的目的:
- 为了介绍十二指肠瘤的PET/CT发现.
- 突出可能导致良性病变被误诊为恶性病变的可能性.
主要方法:
- 一名62岁的妇女接受了18F-FDG PET/CT和68Ga-FAPI PET/CT用于十二指腺质量.
- 图像检测结果与他的病理学相关.
主要成果:
- 18F-FDG PET/CT显示在十二指卵泡的轻度吸收 (SUVmax,3.7).
- 68Ga-FAPI PET/CT在同一病变中显示出强烈的吸收 (SUVmax,9.6).
- 组织病理学证实了一种良性十二指肠瘤.
结论:
- 良性十二指肠瘤可以显示高FAPI吸收,模仿PET/CT上的恶性瘤.
- 十二指肠中的FAPI-avid病变需要仔细解释和考虑良性实体.
- 组织病理学检查仍然是确定确诊的必要条件.
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