与EBNA1结合的MUC1-C自我调节复合体负责隐藏的爱斯坦-巴尔病毒相关的胃癌进展

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Updated: Sep 12, 2025

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Hiroki Ozawa1, Yin Wang2, Henry G Withers3

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.

Oncogene
|August 6, 2025
PubMed
概括

爱斯坦-巴尔病毒核抗原1 (EBNA1) 劫持MUC1-C,通过维持病毒延迟和促进细胞增殖和存活来推动癌症的进展. 准MUC1-C可能会逆转EBV的延迟,并激活病毒溶解周期.

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