药物干预对多学科的失调症团队的贡献:一项追溯观察性研究
Akihito Ueda1,2, Michiko Obara3, Shinichi Watanabe3
1Doctoral Program in Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, Teikyo Heisei University, Tokyo, Japan. akihitoueda@gmail.com.
Journal of pharmaceutical health care and sciences
|August 6, 2025
概括
药剂师可以优化消化不良患者的药物治疗,减少药物负担并预防吸入性肺炎. 他们的专业知识对于多学科的失调症团队至关重要,特别是对于那些服用多巴胺抗剂的人来说.
科学领域:
- 老年学是一门学科.
- 临床药房 临床药房
- 药物监督 药物监督 药物监督
背景情况:
- 日本医疗保健报销变化将药剂师排除在失消症团队之外.
- 与药物相关的吞并发症,特别是与多巴胺抗剂相关的吸入性肺炎,越来越令人担忧.
- 之前的药物监测发现多巴胺阻断药物具有高风险的吸入性肺炎.
研究的目的:
- 为了验证之前关于多巴胺抗剂和失的药监发现.
- 评估药物干预的临床影响,在一个多学科的功能障碍症团队.
- 评估药剂师在管理与药物相关的吞并发症方面的作用.
主要方法:
- 日本社区医院的回顾性观察研究 (2023年6月至2024年1月).
- 包括疑似失的成年患者,接受多学科团队干预.
- 药物干预被分类为:药物诱导的消化障碍管理,剂型优化,吞辅助的使用,以及降低药物负担.
主要成果:
- 59名患有食障碍的患者 (平均年龄为81.1岁);13人 (22.0%) 接受了药物干预.
- 药物诱导的食障碍管理是最常见的 (69.2%),向多巴胺对抗剂,二类药物和抗胆固醇药.
- 干预组显示药物减少显著 (-3.2 药物;P < 0.001);非干预组没有变化.
- 在痴呆症患者中 (38.9%) 药物诱导的消化不良是常见的.
结论:
- 药物干预对失调症患者提供了临床上显著的好处.
- 对多巴胺抗剂的药监工作是相关的;药剂师的专业知识对于药物优化至关重要.
- 对于弱势群体,建议将药剂师恢复到多学科的失调症团队中.
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