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与脂肪组织相关的Krt23+纤维细胞在肥胖的发展过程中,在小鼠脂肪组织中导致免疫微环境障碍

Zhimin Lu1,2, Ling Ding1, Sen Zhang1

  • 1College of Sport and Health, Shandong Sport University, Jinan, 250102, Shandong, China.

European journal of medical research
|August 6, 2025
PubMed
概括

肥胖在中度肥胖阶段引发脂肪组织免疫功能障碍. 特定的Krt23+纤维细胞招募免疫细胞,驱动炎症并改变组织微环境.

关键词:
脂肪组织的脂肪组织.脂肪组织相关的Krt23+纤维细胞 (ATAKFs)免疫微环境是一个微环境.肥胖的阶段 肥胖的阶段

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...