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Updated: Jul 11, 2026

An In Vitro Organ Culture Model of the Murine Intervertebral Disc
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暂时的金黄色葡萄球菌感染通过ATF-3/CHOP通道促进持续的椎间盘退化

Lemeng Ren1, Yichen Li1, Jianlin Yin2

  • 1Department of Orthopedics, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, 200000 Shanghai, China.

Frontiers in bioscience (Landmark edition)
|August 6, 2025
PubMed
概括

过渡性金黄色葡萄球菌感染通过激活ATF3-CHOP通路,导致持续的细胞内膜网膜应激,导致逐渐的椎间盘退化. 准这种途径可能会减轻磁盘退化.

关键词:
激活转录因子3的激活因子细胞内膜网膜的压力应激椎间盘退化 椎间盘退化转录因子 CHOP 的存在.

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