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患有单边和双边口唇裂的患者的喉气道面积和体积分析 - - 一项比较研究
1Department of Oral Medicine and Radiology, School of Dental Sciences, Manav Rachna International Institute of Research and Studies, Faridabad, Haryana, India.
与对照组相比,患有唇裂 (CLP) 的儿童和成年人呼吸道体积和区域较小. 气道尺寸随着年龄的增长而增加,双边裂的成年男性显示出最大的体积.
科学领域:
- 头骨面部异常 头骨面部异常
- 儿科和成人气道解剖学
- 医学中的3D成像技术
背景情况:
- 唇裂 (CLP) 是最常见的头骨面部出生缺陷,在全球约有700例活产中的1例.
- 了解CLP患者的气道维度变化对于管理相关健康问题至关重要.
研究的目的:
- 为了评估与年龄相关的气道尺寸的变化,在儿童和成年人与CLP.
- 将CLP患者的气道尺寸与年龄和性别匹配的对照人群进行比较.
主要方法:
- 一项涉及300个形光束计算机断层扫描 (CBCT) 的横截面观测研究.
- 使用OnDemand 3D软件生成对象气道的3D模型,以计算气道体积和横截面积.
主要成果:
- 与对照组相比,CLP患者的气道体积和横截面积明显较小.
- 单边裂的气道面积比双边裂的气道面积小 (P=0.001).
- 气道体积和面积在裂和对照组中随着年龄的增长而显著增加 (P=0.001).
- 成年双边裂雄性比其他群体的气道体积大得多 (P=0.001).
- 与儿童和对照组相比,双边裂患者在成年人中显示出更大的气道区域.
结论:
- 慢性肺炎与气道尺寸的缩小有关,这些尺寸随着年龄的增长而增加.
- 这些发现对于CLP管理和阻塞性睡眠呼吸暂停治疗的手术规划至关重要.
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