在不同的队伍中,靠近释放设施和认知之间的关联
Scarlet Cockell1, Kelly M Bakulski1, Ai-Lin Tsai2
1Department of Epidemiology, School of Public Health, University of Michigan, 1415 Washington Heights, Ann Arbor, MI, 48109, USA.
medRxiv : the preprint server for health sciences
|August 6, 2025
概括
生活在释放设施附近与老年人的认知功能恶化有关. 这项研究强调了环境因素.
科学领域:
- 环境健康 环境健康
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 已知暴露会损害儿童的认知发展.
- 暴露对不同人群中老年人的认知功能的影响仍未得到充分研究.
研究的目的:
- 调查在两个不同的成年人队伍中,住宅附近与释放设施和认知表现之间的关联.
- 为了确定环境暴露是否是晚年认知能力下降的风险因素.
主要方法:
- 利用了来自两个成年人队伍的数据:凯泽健康衰老和多样化的生活经验 (KHANDLE) 和非洲裔美国人的健康衰老研究 (STAR).
- 评估使用毒物释放库存数据对释放设施的住宅附近情况.
- 使用西班牙语和英语神经心理评估尺度 (SENAS) 测量了特定领域的认知能力,并进行了元分析.
主要成果:
- 更接近释放设施与老年人的认知结果较差有关.
- 具体来说,对于离某个设施更近的每5公里,观察到口头情节性记忆的标准偏差减少了-0.05.
- 在3公里缓冲区内生活与语义记忆和全球认知显著减少有关.
结论:
- 住宅与释放设施的邻近是与老年人认知功能下降相关的重要环境风险因素.
- 这些发现强调了考虑环境暴露在痴呆症预防策略中的重要性.
- 进一步研究认知衰老的环境决定因素是有必要的.
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