超越对抗性:IL-4利用TNF信号来塑造其在单细胞和巨细胞中的基因表达特征

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Using an Automated Cell Counter to Simplify Gene Expression Studies: siRNA Knockdown of IL-4 Dependent Gene Expression in Namalwa Cells
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Published on: April 14, 2010

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Ruoxi Yuan1, Chao Yang1, Bikash Mishra1,2

  • 1HSS Research Institute and David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery, New York, NY.

bioRxiv : the preprint server for biology
|August 6, 2025
PubMed
概括

瘤亡因子 (TNF) 令人惊的是,它能够促进IL-4 (IL-4) 基因表达,而IL-4可选择性地抑制TNF反应. 这种细胞因子交叉,涉及表观遗传机制,促进炎症和组织修复.

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