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西格玛-1受体通过抑制GRIM19促进神经系统中的糖解.

Simon Couly1, Yuko Yasui1, Ioannis Grammatikakis2

  • 1Cellular Pathobiology Section, Integrative Neuroscience Research Branch, Intramural Research Program, National Institute on Drug Abuse, NIH/DHHS, Suite 3512, 333 Cassell Drive, Baltimore, MD, 21224, USA.

bioRxiv : the preprint server for biology
|August 6, 2025
PubMed
概括

西格玛-1受体 (S1R) 通过调节神经元中的糖解和NAD+代谢来调节细胞能量. 失去S1R会减少糖解,改变NAD+/NADH比率,影响大脑的葡萄糖吸收.

关键词:
西格玛-1受体是一个受体.能量代谢 能量代谢葡萄糖溶解是什么线粒体中的线粒体.神经元神经元的神经元尼古丁胺胺腺因二核酸 (NAD) 是一种

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