在CD8+ T细胞分化状态中,STAT5对应物的不对称性和冗余性

Svetlana Ristin1,2, Molly Dalzell1,2, Christopher Armstrong1

  • 1Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, FL, USA.

概括

信号转换器和转录5激活器 (STAT5) 信号传输对于CD8+T细胞免疫治疗至关重要. STAT5B是占主导地位的模拟器,由于其较高的丰度和独特的功能,它比STAT5A具有更大的影响.

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