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Updated: Sep 12, 2025

Using the E1A Minigene Tool to Study mRNA Splicing Changes
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Published on: April 22, 2021

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通过HNRNPH1介导的拼接事件调节了EIF4G1的转录变体组成和AURKA5'UTR的组织

Tayvia Brownmiller1, Soumya Sundara Rajan1, Tamara L Jones1

  • 1Functional Genetics Section, Genetics Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA.

bioRxiv : the preprint server for biology
|August 6, 2025
PubMed
概括

异质核核核糖核蛋白 (HNRNPH1) 调节跨转录组的替代拼接. 这项研究揭示了它在神经母细胞瘤中的作用以及TCF3和AURKA等关键蛋白质的表达.

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