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Updated: Sep 12, 2025

Isolation and Purification of Fungal β-Glucan as an Immunotherapy Strategy for Glioblastoma
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葡萄糖皮质类药物通过抑制GARP/TGF-β轴来释放免疫依赖的黑色素瘤控制

Charles H Earnshaw, Poppy Dunn, Shih-Chieh Chiang

    bioRxiv : the preprint server for biology
    |August 6, 2025
    PubMed
    概括

    葡萄糖皮质醇通过直接降低瘤细胞GARP,抑制TGF-β信号传递并使T细胞死亡,控制黑色素瘤. 这一发现为改善癌症免疫治疗反应提供了新的治疗点.

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