一种NVL的小分子抑制剂通过阻断核糖体生物生成来抑制瘤生长

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Updated: Sep 12, 2025

Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo
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Transfer of Manipulated Tumor-associated Neutrophils into Tumor-Bearing Mice to Study their Angiogenic Potential In Vivo

Published on: July 20, 2019

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Holly H Guo, Ye Tao, Victor E Cruz

    bioRxiv : the preprint server for biology
    |August 6, 2025
    PubMed
    概括

    科学家们发现,抑制核糖体的产生,对于癌细胞生长至关重要,提供了一个新的向疗法. 使用像MM927这样的药物准NVL蛋白质在治疗白血病和结肠直肠癌中显示出有前途,毒性最小.

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