一个序列基因使得在自然酶中广泛使用非正规的氧化辅因子成为可能

Samer Saleh1,2, Ning-Hsiang Hsu3,2, Emma Luu4

  • 1Department of Chemical and Biomolecular Engineering, University of California, Irvine, Irvine, CA, USA.

概括

研究人员在化 aldehyde脱酶 (ALDH) 中发现了一个保存的 RH/QxxR 基因,该基因能够有效地使用非正规的氧化还原因子 (NRC),如尼古丁胺胺 mononucleotide (NMN+). 这一发现开启了生物制造的新可能性,通过扩大酶兼容性以更便宜,可控制的辅助因子.

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