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Updated: Sep 12, 2025

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Published on: September 8, 2021

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RNA加强了染色体上的凝聚核化,以放大瘤转录的转录

Krista A Budinich, Xinyi Yao, Chujie Gong

    bioRxiv : the preprint server for biology
    |August 6, 2025
    PubMed
    概括

    RNA作为瘤性ENL (增强ENL) 凝聚物的关键辅因子,增强它们在癌症中的形成和活性. 在小鼠模型中,破坏这种RNA相互作用会抑制ENL驱动的白血病发生.

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