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Updated: Sep 12, 2025

A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of Caenorhabditis elegans
09:01

A High-throughput Assay for the Prediction of Chemical Toxicity by Automated Phenotypic Profiling of Caenorhabditis elegans

Published on: March 14, 2019

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对环境中毒物暴露的综合性转录基因和表观基因洞察:塔吉特II资源

Bo A Zhang1,2, Benpeng Miao3, Shuhua Fu1,2

  • 1Department of Developmental Biology, Washington University School of Medicine, St. Louis, MO 63108, USA.

bioRxiv : the preprint server for biology
|August 6, 2025
PubMed
概括

早期接触有毒化学物质会导致表观基因组和转录基因组的持久变化. 转录II的基因组和表观基因组调节器 (TaRGET II) 研究的毒素暴露和反应为了解疾病的这些分子基础提供了资源.

关键词:
通过DNA甲基化.疾病的发育起源 (DOHaD)基质子的修改 基质子的修改有毒性与表观遗传学(As) 是一种.双甲 (BPA) 是一种在这种情况下,染色染色素二氧化物 (TCDD) 的使用.基因表达的基因表达方式(Pb) 的使用.颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物 (PM2.5) 颗粒物甲甲酸盐 (DEHP) 的使用三乙 (TBT) 的使用.

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