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Updated: Sep 12, 2025

Techniques to Induce and Quantify Cellular Senescence
06:51

Techniques to Induce and Quantify Cellular Senescence

Published on: May 1, 2017

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准CyclinD1-CDK6以缓解衰老驱动的炎症和与年龄相关的功能衰退

Adarsh Rajesh1, Aaron P Havas1, Rouven Arnold1

  • 1Sanford Burnham Prebys Medical Discovery Institute, Cancer Genome and Epigenetics Program, La Jolla, CA.

bioRxiv : the preprint server for biology
|August 6, 2025
PubMed
概括

环素D1 (CCND1) 和CDK6通过促进衰老细胞中的DNA损伤来驱动衰老中的炎症. 用Palbociclib抑制这种途径可以减少老年小鼠的损伤和脆弱性,从而提供了一个新的治疗点.

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